[hide]1 Clinical use1.1 Indications1.2 Combination with diureticCandesartan is also available in a combination formulation with a low dose thiazide diuretic, invariably hydrochlorothiazide, to achieve an additive antihypertensive effect. Candesartan/hydrochlorothiazide atacand 32 preparations atacand 32 marketed under.

antagonist[edit] IndicationsAs with all angiotensin II receptor antagonists, candesartan is atacand 32 for the treatment of hypertension. The prodrug candesartan cilexetil is metabolised completely by esterases in the intestinal wall during absorption to the active candesartan moieity.The use of atacand 32 prodrug form increases the bioavailability of candesartan. Despite this, absolute bioavailability is atacand 32 poor at 15% (candesartan cilexetil)Metabolism Candesartan cilexetil: intestinal atacand 32 candesartan: hepatic atacand 32 atacand 32 5.1–10.5 hoursExcretion atacand 32 33%, faecal 67%Therapeutic considerationsPregnancy cat. D (Au)Legal status ? Prescription onlyRoutes oralCandesartan (rINN) (pronounced /?k?nd??s?rt?n/) is an angiotensin II receptor antagonists, candesartan is indicated for the treatment of prehypertension appears to be well tolerated and reduced the risk of incident hypertension during the study period. Thus, treatment of hypertension. The prodrug candesartan cilexetil is marketed by AstraZeneca and Takeda.

and mortality reduction benefits of candesartan on mortality and morbidity in patients intolerant of ACE inhibitor.